Can cannabis cure Diabetes?

Diabetes is fast becoming a modern day epidemic. Over the last 30 years the number of sufferers have quadrupled to approximately 422 million worldwide. But studies suggest that the cannabis plant could ameliorate some of the associated symptoms, such as regulating blood sugar levels, reducing neuropathic pain and limiting cardiovascular damage.

What is diabetes?

Diabetes relates to the body’s ability to produce and/or use insulin efficiently. Insulin is a hormone needed to convert glucose into energy. Without it sugar builds up in the blood, which if left untreated has dangerous consequences. Why this happens tells us whether it is diabetes type 1 or 2.

Type 1 Diabetes occurs when the pancreas is unable to produce insulin. It is considered a type of autoimmune disease because the body has destroyed its own insulin-producing cells. The disease usually begins in childhood, with sufferers depending on insulin injections to control blood sugar levels for the rest of their lives.

Insulin-Resistance-1

Type 2 diabetes is by far the most common form of the disease. It is referred to as insulin resistance and is when the pancreas doesn’t produce enough insulin or the body’s cells don’t react to insulin as they should. High glucose levels in the blood are the consequence, sharing the same health risks as type 1: vision loss or blindness, renal failure, cardiovascular disease, and strokes.

Type 2 diabetes is generally adult onset and is associated with obesity, although a study has suggested that it too could be rooted in a misdirected immune response, finding that subjects with insulin resistance produced antibodies against some of their own proteins.

In the initial stages type 2 diabetes can be regulated by dietary changes and exercise, but often eventually requires medication to control glucose levels.

Lying at the heart of both illnesses is an intricate dance between the immune system, excessive inflammation, and oxidative stress. All of which scientists believe can be targeted by compounds found within the cannabis plant called cannabinoids.

Can cannabis help Type 1 Diabetes?

In the case of type 1 diabetes, no amount of cannabis is going to make up for a pancreas that isn’t producing insulin. But it can researchers believe, go some way towards slowing the disease in its early stages, due to the plant’s ability to modulate the immune system and bring into line excess inflammation.

study using Cannabidiol (CBD) administered to mice with early-stage autoimmune diabetes, found the cannabinoid “ameliorates the manifestations of the disease. Diabetes was diagnosed in only 32% of the mice in the CBD-treated group, compared to 86% and 100% in the emulsifier-treated and untreated groups, respectively.” Not only that but pro-inflammatory markers were reduced, the anti-inflammatory cytokine IL-10 significantly elevated, and there were more intact islets in the pancreas, compared to the control group. All of which suggesting that CBD, if administered early enough, “could possibly be used as a therapeutic agent for treatment of type 1 diabetes.”

Another study this time using the psychoactive cannabinoid THC on mice with autoimmune diabetes, found that its administration lowered levels of hyperglycemia, reduced inflammation markers and was accompanied by a decrease in the loss of pancreatic insulin.

So far, no clinical trials testing cannabinoids on human subjects with type 1 diabetes have taken place. In contrast, Type 2 Diabetes has seen research move from the laboratory to humans, with some promising results.

Type 2 Diabetes – Clinical trials show potential for cannabinoids

The British pharmaceutical company specializing in cannabinoid therapeutics GW Pharma, has made avenues into trialling cannabinoids for insulin resistant diabetes. The most successful so far being a randomized, double-blind, placebo-controlled study testing CBD and THCV on 62 non-insulin treated Diabetes type 2 patients. THCV proved the real superstar of the piece significantly decreasing fasting plasma glucose and showing improved pancreatic β-cell function. The study concluded that THCV “could represent a new therapeutic agent in glycemic control in subjects with type 2 diabetes.”

THCV and diabetes

Indeed, a five-year study conducted in the US on the effects of cannabis on fasting insulin and insulin resistance showed that regular cannabis consumers have 16% lower fasting insulin levels and 17% lower levels of insulin resistance than respondents who’d never used cannabis. The scientists also noted a smaller waist circumference in regular cannabis users; all of which suggests that the cannabis plant does have some kind of impact on the body’s metabolic system.

vereating and chronic inflammation

But to really shed any light on why cannabinoids might be a potential therapeutic target for Type 2 Diabetes, we should take a brief look at some of the factors lying behind the disease.

Obesity is commonly stated as a cause of insulin resistant diabetes, but the findings of some Norwegian scientists help explain why this might be. They believe overeating stimulates the immune response, creating excessive inflammation in the body.

The researchers put this down to oxidative stress brought on by damage to the cells’ mitochondria, which are the body’s powerhouses converting glucose to energy.

“When the cells receive excessive energy, the system starts to falter, and the engine may stall. Too much fatty acid causes an oxidative stress in the cells. We believe that long-term stress on the mitochondria may cause metaflammation. A metaflammation is a low-grade chronic inflammation over many years, and unfortunately it’s a condition that’s difficult to detect,” says Yndestad, one of the researchers.

Inflammation is considered a precursor to Diabetes type 2, but is also very much part and parcel of the disease. According to webmd.com, “as type 2 diabetes starts to develop, the body becomes less sensitive to insulin and the resulting insulin resistance also leads to inflammation. A vicious cycle can result, with more inflammation causing more insulin resistance and vice versa.”

CBD reduces inflammation in diabetes studies

The cannabinoid Cannabidiol (CBD) has been shown to be an anti-inflammatory agent and in a study on non-obese diabetic mice there were reduced plasma levels of pro-inflammatory cytokines and increased levels of anti-inflammatory TH-2 associated cytokines, supporting the idea that CBD regulates excessive inflammation. Not only that but the administration of CBD was seen to reduce the incidence of diabetes in the rodent subjects from an incidence of 86% in non-treated control mice to an incidence of 30% in CBD-treated mice.

Could it be that CBD’s anti-inflammatory action was instrumental in reducing the level of diabetes in the trial?

Diabetes complications – oxidative stress a factor

Another potential therapeutic target for cannabinoids and diabetes is protecting against the damage caused by oxidative stress. Often going hand in hand with chronic inflammation, it is when there is an imbalance between the production of free radicals and the ability of the body to counteract their harmful effects with antioxidants.

There is a direct link between diabetes and oxidative stress as hyperglycemia (high blood sugar levels) promotes the formation of free radicals, resulting in complications such as cardiovascular disease, strokes, renal failure, neuropathy and eye diseases like retinopathy.

oxidative_stress_oval

In the paper ‘Antioxidants and Diabetes’ published in the Indian Journal of Endocrinology and Metabolism, it outlines how both Diabetes type 1 and 2 are “accompanied by increased formation of free radicals and decreased antioxidant capacity, leading to oxidative damage of cell components,” and that “hyperglycemia-induced generation of free radicals at the mitochondrial level is thought to be the major driver of the vicious cycle of oxidative stress in diabetes.”

Cannabinoids are powerful antioxidants

When the body can’t produce sufficient antioxidants of its own, the standard course of action is to find them in external sources such as fruit, vegetables, grains, and oily fish. This could be where cannabis comes to the fore, as studies have found it to be a more powerful antioxidant than Vitamins C and E. Indeed the US Federal Government even holds a patent for cannabinoids as antioxidants.

cannabis and diabetes

But an element of caution should be noted, as in general, the effectiveness of antioxidant therapy remains yet to be fully proven. However, it could explain why in many anecdotal cases people claim to have prevented some of the more serious complications associated with diabetes thanks to regular cannabis use.

But what about if you’re already experiencing some of the health conditions associated with diabetes. Can cannabinoids help there too?

Can cannabis relieve neuropathy?

Well, turns out that certain scientific studies suggest they can. Let’s start by looking at neuropathy.

Classified as a type of nerve damage with symptoms such as pain, tingling and numbness in the body’s extremities, it affects up to 70% of diabetes patients.

Preclinical studies testing CBD on diabetes-induced neuropathy in a rat found administration of the cannabinoid “significantly relieved” painful responses to non-painful stimuli and restored the normal perception of pain. Protection of the liver against oxidative stress was also noted, as well as the return to normal of nerve growth factors.

Clinical studies on humans have delivered varying results when it comes to neuropathy. A 2009 studyconducted by GW Pharma testing diabetic neuropathy patients with Sativex, a cannabis-based drug developed for Multiple Sclerosis with a 1:1 THC/CBD ratio, found that the drug was of little more benefit than the placebo.

However, a 2015 study administering THC to diabetic patients with neuropathy of the feet found a “dose-dependent reduction in diabetic peripheral neuropathy pain.”

CBD – Protection against diabetic blindness?

Another common condition affecting long term diabetic patients is retinopathy – the damage to the small blood vessels behind the eye that can eventually lead to the detachment of the retina. It is the leading cause of acquired blindness in developed countries and is caused by the high glucose levels, pro-inflammatory immune response, and oxidative stress associated with the disease.

CBD once again shows promise, with a study carried out on rodent models at the Medical College of Georgia, finding the cannabinoid protected the eye from the accumulation of leaky blood vessels.

Dr Liou the lead scientist explained, “What we believe cannabidiol does is go in here as an antioxidant to neutralize the toxic superoxides. Number two, it inhibits the self-destructive system and allows the self-produced endogenous cannabinoids to stay there longer by inhibiting the enzyme that destroys them.”

As yet, there are no clinical trials on humans to support these findings.

So as ever, there is no conclusive evidence that cannabis and its constituents can treat diabetes. But, the fact that cannabinoids such as CBD are anti-inflammatory, help to regulate the immune response, and are powerful antioxidants, suggest they could show potential for slowing the onset of the disease and its many serious health complications.

Are you diabetic and regularly use cannabis or CBD? We’d love to hear about your experiences in the comments section below. 


Hemp oil or Cannabis oil: THC vs CBD

You’re looking for the oil that you’ve heard has shown so much promise as a medicinal treatment for a wide range of illnesses, but you’re not sure exactly what you should be looking for. The correct response to the question ‘Hemp oil or Cannabis oil’, THC vs CBD, is simple. Hemp oil is cannabis oil – but without the ‘kick’.

To be a little clearer on this question, we need only look at the cannabinoid content of various Cannabis oils. Yes, there are forms of Cannabis oil that are high in THC, the cannabinoid that gave both marijuana and undeservedly, hemp a bad name. But hemp oil contains such low concentrations of THC that you would be highly unlikely to fail a drug test and wouldn’t feel in the least bit high.

THC vs CBD

When making the choice between hemp oil or Cannabis oil with a higher THC level, you should consider the reason why you are seeking Cannabis oil and do a little research online. Both CBD, the cannabinoid most prevalent in hem and THC, the cannabinoid in marijuana have shown promise as treatments for various illnesses.

So much so, that pharmaceutical companies have manufactured synthetic analogs for both of these cannabinoids. The problem with these is that they fail to into account the interaction between THC, CBD and other cannabinoids that are less well researched. There are definitely indications that the combination of natural cannabinoids have a greater effect than any single cannabinoid taken in isolation.

As for the choice between hemp oil or cannabis oil with a higher THC content, these are the questions you should answer:

Are Cannabis oils with a high THC content legal in your country or state?

Have you checked whether CBD could work for the condition you are hoping to treat?

Do you mind the fact that Cannabis oils with a high THC content have the side effect of making you ‘high’ or ‘stoned’?

If you answered ‘No’ to any of these questions, you should definitely do a little more homework before making the choice between hemp oil or Cannabis oil with a higher THC content.

Can CBD do what THC does without the high?

Although THC has received a great deal of research attention, CBD has also been tested for many similar conditions, and has often proved to be effective without the side-effects of THC. For example, medical marijuana containing THC has been proven as a means of managing pain and is widely accepted as a means of treating the nausea caused by chemotherapy. But CBD has shown itself to have similar properties, and doesn’t have the unwanted side effects or the legal issues that surround Marijuana.

It is certainly true that hemp was illegal for a long time, but the sheer folly of banning a useful crop as a ‘drug’ when it has absolutely no psychoactive effects has been recognized, and today, you can get hemp oil legally in many countries and in states across the US without breaking the law.

Hemp oil and hemp oil

Unfortunately, the choice between hemp oil or Cannabis oil isn’t as simple as being aware that hemp oil IS Cannabis oil. You get hemp oils that are high in CBD, but you also get hemp oils that contain much lower percentages of CBD. If you are hoping to use hemp oil as a medicine, you need to know exactly what is in your oil. If you don’t, you have no idea as to how you can dose yourself.

So, to sum up: hemp oil or cannabis oil are the same things, but not all hemp oils are suitable for use as a treatment against illnesses. Do your research, and seek out a high CBD hemp oil with a predictable percentage of CBD. In addition, it is important to ensure that the product you buy is all-natural and organically produced.

CBD and THC – What’s the difference?

Of the many naturally occurring compounds found in cannabis plants, two are of particular interest to researchers. These are CBD (cannabidiol) and THC (tetrahydrocannabinol). These two molecules are of great interest to the medical community; many of whom are calling for further research into its possible uses.

One point that needs mentioning from the get-go is that although CBD and THC can be derived from the same plant, the two cannabinoids are very different. Simply put, CBD doesn’t make you high, while THC does.

Cannabis, Marijuana, and Hemp

There is much confusion as to the differences between marijuana and hemp. Not only are they visually similar in appearance, but both hemp and marijuana are part of the cannabis family. Indeed, both hemp and marijuana strains can be derived from the same species of cannabis, namely cannabis sativa.

For the purpose of this article, references made to marijuana will include strains of cannabis which yield high levels of THC. Conversely, references to hemp will relate to cannabis strains which produce more of the CBD compound and very low amounts of THC that are scarcely detectable.

CBD versus THC

Proponents of medical marijuana want to see high THC cannabis being made available, but the research community regards CBD as a less controversial molecule because of its lack of psychoactive effects. Side effects of THC ingestion often include impaired motor-coordination, a dryness of the mouth and/or a redness of the eyes. Some patients report feelings of paranoia and heart palpitations.

In addition, medicating children with THC is very controversial, not only because of the ‘high’ but also because it may have a negative effect on the developing brain. The North Coaster reports that many of the properties attributed to THC are believed to be present in CBD.

The report looks back at the long history of Cannabis as a medication, even citing a list of ailments for which hemp was believed to hold a cure as listed in a 19th century American pharmacopeia and ancient ayurveda relics of India.

Effect of CBD oil on sleep, mental disorders, immunity, and bowel health

In the introduction to what CBD is good for, we covered the benefits of CBD on the brain, autoimmune disorders and pain. CBD’s extensive benefits can be hard to navigate as they are so extensive. This article only touches the surface of what CBD has the potential to do.

Here in part 2, we delve deeper into CBD’s effects on sleep, mental disorders, immunity, and bowel health.

Is CBD Good for Sleep?

Sleep disorders are often debilitating and controlling, not just of your nights but also the quality of your days. As our lifestyles become busier, we can often struggle to relax and switch off. One of the main causes of insomnia is stress and anxiety, but here CBD can be of help, as it works by regulating your cortisol (stress hormone) levels and inducing a calming effect. Using full spectrum CBD a few hours before bed have by many been reported to be effective in facilitating good quality sleep that is deep and restful.

Here’s list of sleep dysfunction symptoms, where studies have shown that CBD can help:

  • Insomnia
  • Sleep anxiety and stress
  • Sleep apnea
  • REM behaviour disorder
  • Depression
  • Restless leg syndrome

Is CBD Good for Addiction?

Many of the symptoms that are scientifically linked to the benefits of CBD are typically treated with prescription medications that can cause dependency and addiction, like opioids for pain or Xanax for anxiety. CBD has shown promising results in treating people who abuse substances, by reducing withdrawal symptoms and cravings. CBD has powerful antioxidant and anti-inflammatory properties that can protect against the overproduction of glutamate transmissions caused by drug and alcohol addiction, which can result in the brain to having neurotoxicity.

CBD research has shown to aid the treatment of addiction symptoms linked to:

  • Smoking
  • Alcoholism
  • Prescription medication dependency
  • Substance abuse

Is CBD Good for Hormone Imbalance?

CBD stimulates the cannabinoid receptors in your endocannabinoid system. This system influences hormone production by regulating the functions of the pineal, pituitary and thyroid glands. When hormone imbalances occur, it’s usually due to the overproduction of cortisol. If our balance of testosterone and estrogen are out of sync, for example, our bodies go into stress mode. A balance is needed for our systems to stay inhomeostasis. When our hormones are imbalanced, it can affect our overall mood, sex drive and skin.

Here’s list of hormone imbalance symptoms where research indicates that CBD can help:

  • Acne-inflammation
  • Menopause
  • Low sex drive
  • Hormone dominance
  • Fertility

Is CBD Good for your Immunity?

CBD helps subdue inflammation and strengthens the autoimmune system to combat immunity disorders and infections such as colds, flu’s, tuberculosis, and allergies. CBD also works to improve gut health, which is responsible for almost 80% of our overall health. The main receptors for you immune system are found in your gut, and CBD stimulates your endocannabinoid system and its CB1 and CB2 receptors that are responsible for regulating immunity.

Here’s list of immunity conditions where research has shown that CBD could help:

  • Colds
  • Flu
  • Gut health
  • HIV/AIDS
  • Asthma
  • Allergies

Is CBD Good for Digestive and Dietary Disorders?

The endocrine system is in charge of maintaining metabolism and hormones, such as insulin. This is vital in the digestive absorption of nutrients. Insulin is important in regulating blood sugars and converting them into energy, which is why it’s important to keep it at a healthy level. CBD oil works to lower blood sugar levels naturally, and also helps regulate nausea, vomiting and stomach acid regulation. This is done by protecting the throat from stomach acid and reducing inflammation that cause many gut issues.

Here’s list of symptoms of digestive and dietary disorders where research into CBD has shown positive results:

  • Crohn’s Disease
  • Digestion
  • IBS (irritable bowel syndrome)
  • Gut health/leaky gut
  • Diabetes
  • Obesity
  • Chronic intestinal inflammation
  • High blood sugar

If you are wondering how you can take CBD for yourself and the best place to get it, remeber that:

CBD Expert is the ultimate resource to learn about various CBD products and the manufacturing companies.

What diseases can CBD Oil be effective for?

An increasing number of people are turning to all-natural remedies, to take the treatment of their ailments into their own hands, after losing faith in multibillion-dollar pharma companies that claim to have their patient’s best interests at heart. Many see the negative side-effects that are linked to prescription drugs and are looking for other ways to treat their symptoms.

The growing awareness of health and well-being empowers many of us to seek the benefits of natural remedies in the hope of revealing new ways of finding much-needed relief. And one such hope could lie in CBD.

What is CBD?

CBD is often derived from the hemp strain of cannabis, which has little to no THC (less than 0.3%). Historically, hemp plants have been cultivated to be used industrially for clothing and manufacturing. However more recently, because of its high CBD levels and its low THC content, hemp is now being used in the production of CBD oil.

CBD or cannabidiol is one of many cannabinoids found in hemp oil. Hemp oil contains a variety of nutrients, such as plant sterols, terpenes, flavonoids, fatty acids, chlorophyll, and Vitamin E. CBD is purely used for its therapeutic value and doesn’t have any of the ‘high’-inducing effects of THC, therefore making it a great legal and natural alternative to stronger pharmaceutical drugs, that can have negative side effects. When hemp seed oil is sold as food, it often contains very little CBD, while CBD supplements and therapeutic oils contain higher amounts of CBD for supplementary health benefits.

Is CBD Good for Pain Relief?

Those who try CBD are often those that are tired of the side effects of prescription pain medications. They want to try something that is good for their body and doesn’t just treat the symptoms but enhances overall health without adverse side effects.

Studies have shown that CBD reduces inflammation in the brain and nervous system causing less pain responses. As well as inflammation, CBD also helps to stimulate your endocannabinoid system to produce more of the pain fighting cannabinoid, anandamide. CBD works to keep anandamide in your bloodstream instead of being absorbed by the body. This natural compound works to regulate pain, and high levels of anandamide in your bloodstream can reduce pain responses. 

Studies have found CBD to potentially help with the symptoms of conditions such as:

Is CBD Good for Neurological Disorders?

CBD has been known to aid neurological conditions. The majority of medical research has been on the effects of CBD on epilepsy. The most recent studies have been on the effects of CBD on Dravet Syndrome, a rare and extremely hard-to-treat form of epilepsy. Reports have seen reductions in the severity and frequency of seizures, and in some cases, CBD has stopped seizures altogether.

CBD is also thought to eliminate plaque that hinders organ function. This is why CBD could be potentially beneficial to Alzheimer’s patients, because of CBD’s ability to restore communication between the brain and the body helping reduce tremors and aid people in the early stages of Alzheimer’s from losing their ability to recognize familiar faces.

Studies have found CBD to potentially help with the symptoms of neurological disorders such as:

Is CBD Good for Autoimmune Disorders?

Studies into the effects of CBD and autoimmune disorders have shown CBD to protect patients from pathogenesis by the induction of anti-inflammatory pathways.

CBD is a powerful antioxidant which helps fight inflammation by stimulating the vanilloid pain receptors. This inhibits the body from destroying the cannabinoid anandamide by suppressing the Fatty Acid Amide Hydrolase (FAAH).

Studies have found CBD to potentially help with the symptoms of autoimmune disorders such as:

As you can see CBD has a wealth of issues that it can be useful for. These are just some of the conditions where CBD oil can help manage painful and debilitating symptoms.

If you didn’t see any of your ailments in blog, don’t forget to check out this blog. CBD’s list of benefits is so extensive, we had to list them all in two parts. Part 2 has even more of CBD’s benefits, including CBD for sleep function, CBD for stress, anxiety, and depression, and much more.

How to Calculate CBD Content and CBD Oil Price?

When we’re out shopping for groceries, we know how to compare costs. We usually look at price and compare it to the volume or weight of the produce offered, and sometimes it’s even broken down for us. But how do you calculate CBD oil prices? Is a bigger bottle necessarily going to give you a better price?

Ask yourself whether you’re buying carrier oil or whether you’re actually hoping to buy CBD oil. Obviously, since CBD is the active ingredient, the volume of the oil itself doesn’t matter as much as the percentage of the CBD that the oil contains.

It’s no use getting a huge bottle of oil with just about no CBD in it. So how do you calculate and compare actual costs?

Before we go into this, you should remember that CBD oil prices should not be your only consideration. Do look at the quality of the product in terms of where it comes from, how reliable it is and whether it was extracted in accordance with best practice.

At CBD Expert, our primary focus is to research and curate credible information about innovative hemp extracts and to make them accessible worldwide. We are dedicated to understanding the ever-growing CBD market and bring out the honest CBD oil information without compromising on anything.

Bioavailability Matters!

Something that must also be taken into consideration when talking about getting real bang for your buck is bioavailability. Bioavailability is, simply put, how effectively CBD is absorbed into your body and the strength of the compound, when it reaches the site of physiological activity. This is a major component of how beneficial your CBD product turns out to be overall. There are many forms in which CBD is being produced; from suppositories to pastes and ointments, all with different ways of being administered.

So not only is the percentage of CBD within a product important for pricing, but also the strength of the product when it reaches the point in the body where it is needed. The delivery time also depends on the other ingredients within the product, as well as its form and the administration method you choose.

We can say without a doubt that the most bioavailable way to take CBD is in suppository form. For many, the thought of having to manually insert pill-shaped medication into the rectum or vagina can be a little unnerving and even inspire dread, but this method has by far the most bioavailability than any other product on the market so far.

The reason for the high bioavailability in this delivery method is that when medication is left to dissolve in the rectum or vagina, it is able to permeate the thin membrane there, where a network of fine blood vessels carry the CBD straight through the bloodstream to where it is needed. This method is incredibly effective, as it bypasses many of the bodily processes that break down CBD when used sublingually, orally, epidermally, or even through inhalation. This method is also fantastic as it is effective within 10 minutes of insertion; far more rapid than oral administration.

What is the right price of CBD?

How many milligrams of CBD are in a product? If the CBD content is listed as a percentage, you can work this out with the help of some simple calculations. How many milligrams of CBD are you getting? Multiply this out by the percentage to find out how many milligrams of CBD are in the bottle.

So how much does pure CBD oil cost? Supposing you’re considering buying a 10ml bottle of CBD hemp oil that contains 300mg of CBD, if the bottle costs $32, divide this by 300 to work out the price per milligram of CBD. You get an answer of 0.11, so you are paying $0.11 per milligram for a 3% CBD product.

Now suppose you are looking at a 10 ml bottle of CBD hemp oil and you know that there are 1500mg of CBD in the oil. If the CBD oil costs $194, you can divide that by the number of milligrams of CBD you are getting for that price. Your answer is 0.13, so you are paying $0.13 per milligram of CBD.

But if value for money is what you’re after, buying CBD hemp oil suppositories is the product for you. A box of 500mg of CBD will cost you $61, and when you divide this by the milligrams in the product, this turns out to be 0.12, which means the CBD price per milligram is $0.12. This is by far the most cost effective and high bioavailability product we have on the market, so jump on board the suppository train and feel the benefits at a fraction of the cost!

Comparing CBD oil of different strengths

Some other points to note is when to change course and start on a CBD product with a higher percentage of CBD. Going from 3% to 15% CBD products is a big step, so in order to make sure you are being cost effective, you have to be sure that your body needs the higher percentage of CBD. So, how much does CBD oil cost in the 1500 mg products compared to the 300 mg products?

If the 1500 mg product comes in at $194, then the CBD oil cost per milligram would be $0.13, versus the CBD oil cost per milligram for the 300 mg which is $0.11.

It is important to note that because of the higher dosage of the 1500 mg bottle, you would need to titrate it according to what your body needs. To start, you may need to use far less of the 15% than you are used to using for the 3% bottle. This may mean starting with one drop a day and working your way up until you feel the required effects. Remember that your body may not be used to this amount at first, so you may need to be very cautious when beginning with higher percentages of CBD.

CBD Rip-offs Alive and Well

If you’re ready to buy some CBD oil for yourself, having done the math and seen which product gives you the best value for money, don’t click buy just yet. Another point, that some would argue is the most crucial, is where your CBD comes from and the quality of the plant, and therefore the extract of CBD, you are buying.

  • Is your CBD bought in bulk from unregulated companies or in overseas countries, where pollution and bad crops affect the quality of the extract?
  • Does the company provide third party lab tests, attesting to its quality and CBD content?
  • Does the company adhere to Good Manufacturing Practice (GMP) standards?
  • Is your product proven organic?

All these questions are important to think of when you are buying your CBD product. Because anyone who is buying CBD only wants the best and most reliable product.

Some companies rely on a nice, big bottle at a low price for their popularity, but ask yourself what’s in that nice, big bottle. If there’s no specific amount of CBD mentioned, there probably isn’t much in the oil. If a value is listed, find out how the manufacturer arrived at that amount.

Can you view third party laboratory tests?

This might sound like a lot of effort, but if you want to use hemp CBD oil as a therapeutic agent, you need to calculate your dose correctly. Taking too much is a waste and taking too little won’t be effective.

So simply doing some math might not be enough: You also need to do your homework. Is the product manufactured using a clean, professional laboratory or is it from a bucket in someone’s backyard?

Know your hemp oil industry as well as your hemp oil, so you can feel safe in knowing that not only is your CBD hemp oil worth the money, but it’s also efficacious and safe to use.

Can I smoke CBD Oil?

The most common method of CBD consumption remains oral ingestion (either by drops or capsules), but increasingly more and more people are now beginning to explore a whole variety of different ways to consume CBD. Some of these increasingly popular methods can be either by dabbing or by using a vaporizer.

While oils and capsules are a perfectly safe and typical way to consume CBD, it should be noted that you can’t smoke CBD oil. Some people now prefer to smoke or vape CBD, but this method is best consumed with a CBD e-liquid as oil smokes and burns at high temperatures. This new trend of vaping is because the CBD enters the bloodstream at a faster rate through the lung tissue, thus allowing for a quicker and more noticeable effect on the user.

Smoking CBD 

If you are looking for a high concentration of CBD, then smoking CBD form an “oil rig” is one of the most effective ways to achieve this. An oil rig is a device similar to a traditional water pipe, which uses a heated element (usually titanium or quartz), to heat up the CBD e-liquid to a critical temperature. The e-liquid is then vaporized, directed through water filtration for cooling, and then inhaled by the user in a large concentration. This produces a smoother smoke that is not as thick as a cannabis-plant smoke, however it can be a little ticklish on the throat and may induce some coughing.

Dabbing is another common method of smoking CBD that is increasingly gaining in popularity thanks to it’s powerful and rapid effect. This method of consumption allows you to enjoy CBD in its purest form. Using a CBD concentrate in this form is a really effective way of harnessing the effects of CBD. Users who use CBD in this form swear by its rapid effectiveness and potency. New users should use caution, though, when dabbing for the first time, as this consumption method is far stronger than capsules or oils. Although you won’t overdose on CBD, consuming an excessive amount via dabbing could result in an uncomfortable experience.

Vaping CBD

Vaping CBD is one of the easiest methods of consuming CBD and also one of the healthiest when it comes to absorbing CBD via your respiratory system.

Vaporizing has rapidly emerged as the preferred method for CBD consumption among health-conscious CBD users with an increasing amount of people swapping their cigarettes for a CBD vape pen. Indeed, using a vaporizer (or vape pen) is now one of the most common methods of CBD consumption thanks to its convenience, discretion and fast effects.

What Is a Vaporizer?

A vaporizer is a device that uses convection or conduction to precisely and evenly heat your CBD. This process produces a pure, clean vapor that can be safely inhaled to absorb the natural health benefits of your CBD.

For people with chronic pain or other conditions treated with CBD, vaping provides a convenient and almost instant relief that you might not achieve when taking CBD in capsule or oil form. Many users do describe an almost instantaneous effect when they first vape CBD, so if you need a fast and effective relief from pain, vaping could well provide the solution.

This method of consumption also allows users to remain discrete and consume CBD in public, while also offering fast and effective relief as the CBD enters your bloodstream at a quicker rate than via either capsule or oil. With so many people now looking to quit smoking (cigarettes), CBD vaping provides a healthier alternative that is now increasing rapidly in popularity, all thanks to the multitude of potential benefits that CBD can provide.

Benefits of Smoking or Vaping CBD

Smoking a cigarette is probably one of the most pointless things a human being can do in 2018, but sadly millions of people remain addicted to a substance that killed 6 million people last year. Such numbers are truly barbaric and devastating to our society. However, millions of people remain hooked in spite of all the deadly information that is so readily available to us today.

One of the main problems, of course, is that smoking is incredibly difficult to quit. Thankfully, alternatives to smoking are now available and one of the best ways to help you quit smoking is by vaping CBD. There is actually some really promising evidence that CBD use may help people to quit smoking. One pilot study found that smokers who used an inhaler containing CBD smoked fewer cigarettes, but did not have any additional craving for nicotine. Not only are you getting rid of those horrible cigarettes, but you will actually replace a killer substance with one that can actually help to heal you. That makes sense right?

So many smokers claim to enjoy a cigarette because they suffer from stress, anxiety or nervousness. They may even just enjoy the feeling of holding something in their fingers when in public. Now, by vaping CBD, you can actually help to treat your anxiety, avoid cancer and still continue your habit of holding something in between your fingers!

When you vape CBD, the CBD enters your lungs and diffuses directly into your bloodstream rather than passing through your gut and liver. This process allows for nearly four times as much CBD to enter your circulation as compared to oral ingestion. Basically, this means you can achieve the same beneficial effects with a much smaller dosage of CBD.

Vaporizing devices are also quick and convenient, allowing you to take small “hits” of CBD throughout the day as opposed to taking a pill or oil in the morning or evening. This allows you to control your intake of CBD throughout the day or to have it available when you need it most.

So, while you can certainly smoke CBD, there are so many different options now available that give CBD users the freedom to reap the benefits at their pleasure and convenience.


Where can you travel with CBD Oil?

With the increasing number of people now using CBD oil and other products, it has become important to answer whether it is actually legal and safe to travel with CBD oil?

Like most things, the answer is not exactly straightforward with many countries yet to fully embrace the CBD revolution that is currently engulfing much of the planet today.

While other liberal, forward-thinking countries like Canada and The Netherlands have legalized both medical and recreational cannabis, many countries still adhere to laws that could best be described as outdated.

So, if you have a trip planned in the coming weeks, here is a guide to the legality and safety of travelling with your CBD oil or CBD hemp oil to some of the major tourist destinations across the world.

Travel to Australia with CBD?

While Australia legalized medical cannabis in 2016,travelling down under with CBD oil remains somewhat tricky with the government yet to form any real degree of clarity for tourists.

Australia’s Department of Immigration and Border Protection state that you do NOT need a permit to bring in most prescribed medicines, even if they contain a controlled substance but a valid prescription is absolutely mandatory.

The TGA (Therapeutic Goods Administration) has also stated that anyone travelling to Australia (including Australian residents) who hold a valid prescription for CBD may enter the country with a three-month supply of CBD hemp oil.

However, the TGA also emphasized that CBD oil that contains THC is not permitted “Cannabis plant material (e.g. flowers, leaves) or products containing THC are not permitted entry with travellers to Australia.”

The Office of Drug Control in Australia also states that “travellers with CBD oil should email DCS@health.gov.au to clarify whether they can travel with their medication,”

Despite medical cannabis being legal in Australia, If you do try to enter the country with a CBD product that contains THC, even if lawfully prescribed, you may find yourself in a sticky situation (and not just because your CBD leaked all over your suitcase!)

So, ultimately, it is possible to enter Australia with CBD oil, but only if you have first emailed the government, and it contains no THC (less than 0.2%) and has been prescribed by a Doctor.

Travel to Singapore with CBD?

Singapore is one of the most-visited destinations in the world and their country carries some of the harshest drug penalties on the planet.

Unfortunately, CBD oil is treated in the same regard as cannabis and it remains illegal to enter the country with any CBD products whether they contain THC or not.

Despite Singapore’s recent analysis of whether it is possible to use the therapeutic compounds found in cannabinoids to create legitimate medicines, the country still continues to adopt a hardline approach to CBD usage, so if you are planning on either going to Singapore, or briefly stopping off on your way to Australia, you will have to leave the CBD at home.

Narcotics officers working at Changi Airport are specifically on the look-out for anyone they suspect of not only carrying drugs but even for people who have may have used drugs in the previous days.

If you are suspected of drug use, it is possible for narcotics officers to take you into custody, and demand a urine test (without your permission) and while CBD hemp oil is highly unlikely to ever cause a positive test for cannabis, CBD oil that contains THC could do just that.

Anyone testing positive for cannabis could then be prosecuted and first time offenders (someone who tests positive for cannabis usage) could expect at least 1 year in a Singaporean jail, even if they have consumed the drugs before entering the country.

Under the Misuse of Drugs Act, the prescribed penalties for possession of even minuscule amounts range from fines of up to $20,000 to a maximum of ten years in prison while those convicted of trafficking offenses will be sentenced to death. Yes, really.

Travel to U.A.E (Dubai) with CBD?

Over the past 20 years, Dubai has emerged as one of the world’s favorite tourist destinations, but much like Singapore, their drug laws remain some of the scariest on the planet and it may be tricky to enter U.A.E with CBD oil, even if prescribed and even if it contains no THC.

The United Arab Emirates (UAE) has a very strict, zero-tolerance anti-drugs policy and conducts thorough searches at its airports, using highly advanced equipment.

Travellers to Dubai have found themselves spending years in jail for the possession of just 3 milligrams of cannabis. That equates to a pinhead-sized speck, detected by swabbing a person’s shoes.

Possession of even tiny amounts of illegal drugs has resulted in severe punishments for travellers entering or transiting the UAE.

If you were to test positive for cannabis in the Emirates, you could be jailed for 4 years, even for mere trace amounts of cannabis metabolites consumed before you entered the country.

A British man was recently sentenced to two years in an Emirates jail having failed a drug test in the Emirates because of consuming cannabis in the UK before travelling.

As it stands cannabis is considered a narcotic and therefore illegal under all circumstances, However, the cannabinoid THC is considered a controlled medicine, in which you can apply for a permit to carry it if it’s for medical use.

Contact the United Arab Emirates Ministry of Health and Prevention, if you are thinking of travelling with CBD, a prescription issued by an attending physician, a medical report approved by health entities and a copy of Emirates ID or passport will be needed.

The quantity you want to carry should not exceed your personal need for a 3 month period. The best advice would be to contact the United Arab Emirates Ministry of Health and Prevention and consult the Sharjah customs Department of Seaports and Customs. I wouldn’t even think about travelling with CBD without checking with the government first, this also goes for CBD hemp oil too, as the laws on the compound cannabidiol are not clear.

Travel to Europe with CBD?

At present, Europe is certainly one of the safer places where one can travel with CBD, with many countries now legalizing medical cannabis as the CBD boom gathers pace across the Atlantic.

If you are traveling with a CBD hemp oil, you will be safe to travel to any of the following countries:

  • Austria
  • Belgium
  • Bosnia and Herzegovina
  • Bulgaria
  • China
  • Croatia
  • Cyprus
  • Czech Republic
  • Denmark, Estonia
  • Finland
  • France
  • Georgia
  • Germany
  • Greece
  • Hong Kong
  • Hungary
  • Iceland
  • India
  • Ireland
  • Italy
  • Latvia
  • Liechtenstein
  • Lithuania
  • Luxembourg
  • Malta
  • Netherlands
  • Northern Ireland
  • Norway
  • Poland
  • Portugal
  • Romania
  • Russia
  • Slovakia
  • Slovenia
  • Spain
  • Sweden
  • Switzerland
  • United Kingdom

Clearly, there are many dangers and hazards when travelling to different parts of our world and if you are someone who really needs to use CBD oil on a daily basis, you really need to research which countries will allow you to enter with your CBD before confirming any trips overseas.

Despite the incredible advancements in CBD usage and acceptance that we have witnessed in recent years, it is obvious that many countries have yet to adopt a similar mentality.

Ultimately, it really is important to be sensible, check with the embassy or consulate of the country in which you are visiting and always, I repeat, always make sure to do the appropriate research in advance of your trip overseas.

Sadly, there are a number of innocent CBD or medical cannabis users who, through little fault of their own, have been victim to the harsh and downright terrifying laws adopted in some of our favorite holiday destinations. Don’t let it happen to you.

How to buy CBD online?

As the cannabis compound, Cannabidiol (CBD) gains more and more recognition for its potential therapeutic benefits, it also becomes more and more difficult to navigate this fairly new and somewhat unregulated industry. When faced with a vast amount of choice, it can seem somewhat overwhelming to say the least for consumers to know how to find the best quality CBD on the market. 

So how do you Make the Best CBD Choice? When there is so Much Choice!

CBD’s potential to treat a wide variety of ailments including stress and inflammation, coupled with its non-psychoactive properties, makes it a great legal option for those that want to take a more natural approach to treat their symptoms. There are now an array of products that are available on the CBD market, from chewing gum to CBD water and even skin care products.

Legality

When CBD is derived from the hemp plant it is considered legal in most places, because of the low content of the psychoactive cannabis compound THC (0.2%). In most places globally THC is deemed illegal with a few exceptions. If you are thinking of buying CBD oil it would be wise to check the legality of the country you reside in before making your purchase, luckily for those that that live stateside CBD derived from hemp is legal in all 50 states. However, if you live in Australia, Brazil, Singapore or Dubai, you will have to have a valid prescription before you can even think about taking CBD even if its derived from hemp.

Researching the Best Places to Find CBD Oil for Sale

There are many CBD vendors out there that are willing to take advantage of CBD’s rapidly growing popularity and unfortunately sometimes offer low-quality CBD products with a high price tag. It can be frustrating navigating the maze of webshops and companies that all claim to have the best products. Many look out to taking your money and only a few sites are genuinely willing to offer helpful advice.

So, who can you trust? Let’s face it CBD oil isn’t cheap, so buying CBD oil online for a newcomer can seem risky and a professional looking website doesn’t always mean the people behind it are legitimate. It’s important that you carry out a few sensible checks before finalizing your purchase!

Here are a few steps to help you find the best CBD oil for sale:

1. Research & knowledge

Knowledge is power so researching is essential to understand exactly what you are looking for when buying the best quality CBD oil when you understand exactly what you are buying you will be able to make the best decisions about the type of CBD product you need.

Initial things you need to consider and understand before buying CBD oil:

What are cannabinoids- the difference between CBD and THC?

What are the potential benefits of CBD oil?

Where CBD is derived from -Hemp or Cannabis?

ProjectCBD.org is a good starting point. 

*Beware of false medical claims: Be very wary of any company that makes strong medical claims or who try to give you medical advice regarding CBD. This goes directly against the current FDA guidelines, even though CBD Oil has many anecdotal health benefits, in most countries making medical claims about CBD is against the law.

2. Choose Reputable CBD Oil Brands

The CBD market can be hard to navigate and has become saturated in a very short space of time, making it hard for consumers to know how to pick the best brand. Some claim to sell a high-quality product, but in fact, contain very little to no CBD at all.

Others also mislead consumers by using synthetic CBD or CBD isolate mixed with a carried oil and pass it off as the best quality. It should be noted that there is nothing wrong with the isolated compound CBD on its own as it has its own benefits and uses. However, the wealth of benefits that can be achieved with a broader spectrum CBD oil that contains cannabis’ plant terpenes and minor phytocannabinoids can be potentially much greater. 

While browsing for CBD oil, it’s worth paying attention to the source and content of the oil, and if it has been thoroughly tested and shows lab results, so you can ensure the origins of the product.

You can either buy CBD oil directly online from a supplier like Endoca or you can find a reseller who stocks high-quality CBD. Buying directly from a producer can sometimes work out cheaper but this isn’t always the case.

A reseller can be a better choice if the legality of CBD is in question in your country or you don’t want to go through the risk or hassle of importing CBD through customs or across state lines. It’s always a good idea to ring the company up to check where their shipping facilities are located.

You also want to ensure the company offers you good customer support and answers your questions. Make sure the company gives all their contact details, try calling them up or shooting them an email and see what response you get.

3. Look for Quality over Price

With so many products only one click away, it can be tempting to choose the most affordable CBD oil you can find; but it’s important to remember cheaper is not necessarily better.

There are a few factors to consider when comparing the quality of different CBD oil manufacturers. The price you pay may reflect this. 

Here are some of the factors to consider when looking for a reputable CBD brand: 

  • Extraction Method – The production method used for extraction can massively affect the quality of the oil, the Supercritical CO2 method is the cleanest and produces the best quality oil. Other methods include Solvent Extraction or CBD isolate in a carrier oil.
  • Organic vs Non-Organic – Non-organic CBD oils may contain heavy metals and other toxins from the soil or may have been treated with pesticides in the growing process. Choose a brand that is organically certified to ensure its really organic!
  • Safe and GMP (Good Manufacturing Practices) Certified- This ensures the company takes the necessary safety precautions when handling and processing the CBD oil.
  • Lab Testing and 3rd Party Lab Testing – Never buy CBD unless you can see the Lab test results showing the exact percentage of CBD inside the product. Most good companies publish their results online. They also carry out 3rd party testing too with an external lab, for an extra guarantee. The tests show results for pesticides and heavy metals, microbial organisms, fungus, mold, and other impurities.
  • Online Reviews – Check out sites like cbdexpertTrustPilot, etc. for independent customer reviews. You can find out about different CBD brands on sites like at CBDNerds.com

4. Choose the Best Method consume CBD for you

CBD is a healthy and extremely versatile natural substance that can be consumed in numerous different ways that can potentially help with a range of health benefits.

CBD oil is probably one of the most popular ways to take the compound CBD. But there are a few things to consider when choosing the best method of taking CBD. As the industry grows rapidly, so do the amounts of products that are available on the market. There is now a vast array of products to choose from, these range from CBD water to CBD chewing gum, and while new innovation can be good and new products pop up on the scene all the time. New doesn’t always mean better, we recommend you stick to looking for quality over fads.

It is also important to know the advantages and disadvantages of administering CBD in different ways. Different CBD product types offer different benefits and come with various advantages. For example, some CBD oil products are more potent in terms of CBD concentration and others focus more on ease of use to allow consumers to take them on the go without hassle. Some products have tasty flavors while others consist of pure CBD oil that packs a stronger punch.

You may want to consider the following:

What strength do I need?

What method would suit me best?

Do I want quick relief or slow release?

Is the CBD oil full spectrum or the isolated compound?

Here’s a guide to help you weigh up the pros and cons and choose the right product for you:

CBD Oil

CBD Oil is one of the most popular and arguably the most versatile forms of CBD products available today.

CBD Oil Drops make measuring and adjusting the dosage easy because you can easily increase or decrease your dosage by using the dropper.

CBD Oil Drops are absorbed under your tongue (sublingually), which means that they act quicker than other formulations.

High-quality CBD oil can be available with the full spectrum of minor- cannabinoids, terpenes and plant waxes. It is thought that when the full spectrum of cannabinoids that are found naturally in the plant are present in the oil, they work better together, this is called the entourage effect. 

CBD Extract

CBD extract is a high concentrate of CBD and can come in the form of a paste. It is designed to be taken orally and doesn’t have any added flavors or sweeteners.

This high concentration of CBD Oil is ideal for consumers who need a strong dose. It is not recommended for new CBD curious users who may have mild symptoms.  

CBD Capsules

These are standard dissolvable capsules that contain hemp oil with different concentrations of CBD. The CBD capsules are perhaps the best type of CBD product for sale in terms of ease of use and come with a number of added conveniences.

Capsules make it easy to keep track of your daily dosage. Each package comes with a specific number of capsules (for example, Endoca offers you 30 capsules per package), so when in doubt, you can quickly check whether you’ve taken your daily dosage or not.

However, CBD capsules offer you limited options when it comes to increasing your dosage in small amounts.  However, you can offset this limitation by combining more than one of our CBD products to adjust your daily dosage. For example, you could use one capsule plus a CBD oil product to optimize your daily dosage.

CBD capsules are also slow release and don’t work as fast as taking the oil sublingually, Ingesting CBD capsules means it takes longer for CBD to be absorbed into your system, and is ideal for those that want a long lasting effect over time.

If you want to understand more about how CBD is absorbed, read our article on CBD and bioavailability to understand how different methods affect CBD’s absorption.

CBD Vape

Vaporizing CBD is becoming increasingly popular as it’s a very quick and effective delivery method, especially if you are using CBD for conditions like anxiety. It allows you to regulate your dosage easily because CBD is absorbed directly through the lungs. It’s important that you pick a high-quality e-liquid when ingesting CBD this way.

You can vape CBD by using CBD crystals/isolate or a high-quality CBD e-liquid. It should be noted that you can’t smoke CBD oil when oil is heated at high temperatures it smokes, which is not good for your vaporizer or your body. 

 99% pure cannabis crystals that are ideal for vaping. Crystals consist of only the isolated CBD compound, so therefore they don’t give the benefits of the ‘entourage effect’ which occurs when the full spectrum of minor cannabinoids and terpenes are present, like in our Raw CBD extracts and oils. You can also add crystals to your edibles or teas.

CBD Suppositories

If you are suffering from nausea and vomiting or other gastrointestinal issues, CBD suppositories allow you to be sure that your CBD is absorbed into your body. Suppositories also allow for faster action and prolonged release of CBD into the bloodstream.

Suppositories are made from natural coconut oil that has been infused with CBD oil. They can be taken anally or vaginally and will also give a slow release over time. 

Still not sure what’s Best for you?

Check out other blogs on cbd Expert to make an informed choice about CBD Oil.